Evidence-based nutrition

Precision nutrition for whole-body support™

We believe everything is interconnected. Nature does not exist in isolation. Nor does our body.

non-gmo

NON-GMO

gluten-free

GLUTEN-FREE
CERTIFIED

fodmap

FODMAP
FRIENDLY

halal

HALAL

sqf

SQF
CERTIFIED

nsf

NSF cGMP

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PUBLIC BENEFIT
COMPANY

plastic-neutral

PLASTIC
NEUTRAL

third-party

THIRD-PARTY
TESTED

non-gmo

NON-GMO

gluten-free

GLUTEN-FREE
CERTIFIED

fodmap

FODMAP
FRIENDLY

halal

HALAL

sqf

SQF
CERTIFIED

nsf

NSF cGMP

pbc

PUBLIC BENEFIT
COMPANY

plastic-neutral

PLASTIC
NEUTRAL

third-party

THIRD-PARTY
TESTED

non-gmo

NON-GMO

gluten-free

GLUTEN-FREE
CERTIFIED

fodmap

FODMAP
FRIENDLY

halal

HALAL

sqf

SQF
CERTIFIED

nsf

NSF cGMP

pbc

PUBLIC BENEFIT
COMPANY

plastic-neutral

PLASTIC
NEUTRAL

third-party

THIRD-PARTY
TESTED

Shop ACEND

Whole-body support starts
with the system.

Formulations designed around interconnected biological pathways, not isolated symptoms.

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ACEND-CI stick pack and box

PRECISION NUTRITION

ACEND-CI

Precision-formulated for the dietary management of chronic inflammation and systemic inflammatory balance.

Pineapple flavor  ·  15 packets  ·  HCPCS code A9153

From

$49.50

In development

More precision formulas are on the way.

Built with the same systems-biology approach. Be first to hear when they launch.

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Systems biology

Treat the system, not just the symptom®

Chronic inflammation rarely lives in one place. ACEND-CI supports multiple pathways in one daily protocol.

01

Inflammatory signaling

Evidence-based polyphenols and bioactives that support healthy inflammatory signaling.

02

Gut barrier + microbiome

Supports a strong gut lining and a balanced microbiome.

03

Oxidative stress balance

Helps maintain cellular balance against everyday oxidative stress.

04

Mitochondrial resilience

Supports energy production at the cellular level.

35

evidence-based
ingredients

EXPLORE THE SCIENCE

Why it matters

Inflammation is connected to everything.

Low-grade, chronic inflammation is linked to metabolic, gut, cardiovascular, immune and hormonal health. ACEND-CI is a synergistic formula designed around the interconnected pathways involved in chronic inflammation.

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Gut barrier + immune signaling

The gut helps set immune tone. When the barrier is strained, inflammatory signaling can amplify system-wide.

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Metabolic-inflammatory tone

Inflammatory load can disrupt metabolic steadiness, affecting energy balance and daily recovery.

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Brain-body resilience

Inflammation can shape brain-body communication, influencing stress regulation and perceived resilience.

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Our standard

One uncompromising standard.

01

Biology-first formulation

Built around how interconnected pathways work in the body.

02

Clinically informed design

Every ingredient is there for a reason, at a meaningful dose.

03

Radical Integrity®

Clean labels and certifications. We never exaggerate, overstate or mislead.

04

Absorption where it matters

Advanced delivery technologies help ingredients reach where they work.

05

Plant integrity + responsible sourcing

Thoughtfully sourced ingredients in plastic-neutral packaging.

Your first 12 weeks

ACEND-CI combines evidence-based polyphenols, targeted bioactives and micelle delivery technology in one daily serving. Here’s how to build the routine.

Weeks 01 – 02

Build the habit

Take one or two stick packs per day, depending on your protocol, mixed with water. Consistency matters more than timing.

Weeks 03 – 06

Stay consistent

Take ACEND-CI at the same time each day, like with breakfast, so it becomes part of your routine.

Weeks 06 – 12

Keep it going

Most protocols run 90 days. Subscribe so you never run out.

Customer stories

Real people, real routines.

★★★★★

“It’s working!”

I like it. Feeling better. More energy. Less aches and pains.

Edward G. · Verified buyer

★★★★★

“If I could leave 10 stars, I would!”

After two weeks I can say that I definitely feel a difference.

Susan W. · Verified buyer

★★★★★

“Shake it!”

My doctor told me about ACEND. I noticed a difference after about 7 days.

Erin R. · Verified buyer

Customer-reported experiences. Individual results vary.

The journal

Explore the science behind inflammation.

Article image

Science

Inflammation’s role in disease

Inflammation is essential to healing, but when it becomes chronic it may contribute to metabolic, cardiovascular, immune, gut and cellular dysfunction.

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Ingredients

Polyphenols and the gut microbiome: a two-way conversation

Many polyphenols reach the colon, where gut microbes transform them into new compounds, while the polyphenols may help shape the microbial ecosystem.

For practitioners

Clinical resources, all in one place.

Clinical data sheets, mechanisms, dosing rationale, safety and interactions, and patient-use guidance, through the ACEND practitioner portal.

✓ Clinical data sheets + citations
✓ Dosing rationale + patient guidance
✓ A direct line to our clinical team

Illustrated cells